Biotage AB launches share buy-back
Resolutions at the Annual General Meeting in Biotage AB on April 25, 2013
Interim report January - March 2013
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Published Articles Synthesis
Literature References
Parallel Modification of Tropane Alkaloids Aberler, N. S.; Ganesan, A.; Lambert, J. N.; Saubern, S.; Smith, R. Tetrahedron Letters, 2001, 42, 1975-1977. Related products: PS-Trisamine, PS-Triphenylphosphine, MP-Carbonate
A Polymer Bound Iminophosphorane Approach for the Synthesis of Quinazolines Zhang, W.; Mayer, J.P.; Hall, S. E.; Weigel, J. A. J. Comb. Chem. 2001, 3, 255-256 Related product: PS-Triphenylphosphine
Mitsunobu Reaction Modifications Allowing Product Isolation Without Chromatography: Application to a Small Parallel Library Pelletier, J.C.; Kincaid, S. Tetrahedron Letters, 2000, 41, 797-800. Related product: PS-Triphenylphosphine
Michael Reactions in Water Using Amphiphilic Resin-Supported Quaternary Ammonium Hydroxides Shibatomi, K.; Nakahashi, T.; Uozumi, Y. Synlett, 2000, 11, 1643-1645. Related product: ArgoGel
Mitsunobu Reaction Modifications allowing Product Isolation Without Chromatography: Application to a Small Parallel Library Pelletier, J. C.; Kincaid, S.; Tetrahedron Letters, 2000, 41, 797-800. Related product: PS-Triphenylphosphine
Macrolactonization of Hydroxy Acids Using a Polymer Bound Carbodiimide Keck, G. E.; Sanchez, C.; Wager, A. Tetrahedron Letters, 2000, 41, 8673-8676. Related product: PS-Carbodiimide
Parallel Solution Phase Synthesis of N-substituted 2-pyrazoline Libraries Bauer, U.; Egner, B. J.; Nilsson, I.; Berghult, M.; Tetrahedron Letters , 2000, 41, 2713-2717. Related Products: PS-DIEA,PS-Trisamine,PS-Isocyanate
Alternative Base Matrices for Solid Phase Quenching Reagents Nicewonger, R. B.; Ditto, L.; Varady, L.; Tetrahedron Letters, 2000, 41, 2323-2326. Related product: MP-Trisamine
Oxazoline Synthesis from Hydroxamides by Resin Capture and Ring-Forming Release Pirrung, M. C.; Tumey, N. L.; J. Comb. Chem. 2000, 2, 675-680. Related product: PS-TsCl
Facile Solid-Phase Construction of Indole Derivatives Based on a Traceless, Activating Sulfonyl Linker Zhang, H. C.; Ye, H.; Moretto, A. F.; Brumfield, K.; Maryanoff, B. E.; Organic Letters, 2000, 2, 89-92. Related product: PS-TsCl
Multistep Solution Phase Parallel Synthesis of Spiperone Analogues Hansen, H.C.; Olsson, R.; Croston, G.; Anderson, C. M.; Bioorganic and Medicinal Chemistry Letters, 2000, 10, 2435-2439. Related product: PS-TsCl
Use of Polymer Supported Thiophenol for the Synthesis and Purification of a Benzimidazol-2-one Library Ermann, M.;Simkovsky, N.M.; Roberts, S. M.; parry, D. M.; Baxter, A. D.; Montana, J.G. Tetrahedron Letters, 2000, 41, 2483-2485. Related product: PS-Thiophenol
A Convenient and Scalable Procedure for Removing the Fmoc Group in Solution Sheppeck, J. E.; Kar, H.; Hong, H. Tetrahedron Letters, 2000, 41, 5329-5333. Related product: PS-Thiophenol
Use of Polymer Supported Thiophenol for the Synthesis and Purification of a Benzimidazol-2-one Library Ermann M., Simkovsky N.M., Roberts S.M., Parry D.M., Baxter A.D. and Montana J.G, Tetrahedron Letters 41, 2483–2485 Related product: PS-Thiophenol
Synthesis of Enamides Related to the Salicylate Antitumor Macrolides Using Coper-Mediated Vinylic Substitution Shen R., Porco J.A., Organic Letters, 2000, 2, 9, 1333-1336. Related product: Quest 210
Polymer-Supported Silyl Cyanide and Silyl Azide: Useful Reagents for Solid-Phase Applications Missio A., Marchioro C., Rossi T., Panunzio M., Selva S., Seneci P. (GlaxoWellcome Medicines Research Centre, Verona (Italy)) Biotechnology and Bioengineering, 2000, 71, 1, 38-43. Related product: PS-DES
Kinetic Comparison of Trifluroroacetic Acid Cleavage Reactions of Resin-Bound Carbamates, Ureas, Secondary Amides, and Sulfonamides from Benzyl-, Benzhydryl- and Indole-Based Linkers Yan, B; Nguyen, N; Liu, L.; Holland, G. Raju, B. J.Comb. Chem. 2000, 2, 66-74. Related product: PS-Indole-CHO, PS-MB-CHO
Synthesis of Highly Substituted 5-(Trifluoromethyl)ketoimadazoles Using a Mixed-Solid/Solution Phase Motif Hamper, B.; Jerome, K.D.; Yalamanchili, G.; Walker, D.M.; Chott, R.C. Mischke, D.A. Biotechnology and Bioengineering (Combinatorial Chemistry), 2000, 71, 1, 28-37.
Polymer-Supported Silyl Cyanide and Silyl Azide: Useful Reagents for Solid-Phase Applications Missio, A.; Marchioro, C.; Rossi, T; Panunzio, M.; Selva, S.; Seneci, P. Biotechnology and Bioengineering (Combinatorial Chemistry), 2000, 71, 1, 38-43. Related product: PS-DES
Polymer-Assisted Solution-Phase (PASP) Library Synthesis of a -Ketoamides South, M.S.; Dice, T.A.; Parlow, J.J. Biotechnology and Bioengineering (Combinatorial Chemistry), 2000, 71, 1, 51-57. Related product: PS-Carbodiimide, PS-Trisamine
The following papers are among recent publication references that report successful use of resin-bound reagents and scavengers in microwave-assisted synthesis.
Increasing Rates of Reaction: Microwave assisted Organic Synthesis for Combinatorial Chemistry Lew, A; Krutzik, P.O.; Hart, M.E.; Chamberlain, A. R.; J. Combi. Chem. 2002, 4, 95-105.
Synthesis of 1,3,4-Oxadiazoles Using Polymer-Supported Reagents Brain, C.T.;Synlett 2001, 382-384.
An Efficient Combination of Microwave Dielectric Heating and the use of Solid-Supported Triphenylphosphine for Wittig Reactionse Westman, J.; Org. Lett. 2001, 3(23), 3745-3747.
A Polymer Supported Thionating Reagent Ley, S.V.; Leach, A.G.; Storer, R.I.; J. Chem. Soc. Perkin Trans 2001, 4, 358-361.
Thermal and Microwave Assisted Hydrogenation of Electron-deficient Alkenes Using a Polymer-Supported Hydrogen Donor Desai, B.; Danks, T. N.; Tetrahedron Letters, 2001, 42, 5963-5965.
A Polymer-Supported [1,3,2] Oxazaphospholidine for the Conversion of Isothiocyanates to Isocyanides and Their Subsequent Use in an Ugi Reaction Ley, S. V.; Taylor, S.J.; Bioorg. Med. Chem. Lett. 2002, 12, 1813-1816.
Fast Microwave-assisted Preparation of Aryl and Vinyl Nitriles and the corresponding Tetrazoles from Organo-halides Alterman, M.; Hallberg, A.; J. Org. Chem. 2000, 65, 7984-7989.
Rapid Parallel Synthesis Utilizing Microwave Irradiation 8. Glass, B.; Combs, A.P.; In High-Throughput Synthesis. Principles and Practices; Sucholeiki, I., Ed.; Marcel Dekker:New York, 2001, pp 123-128.
High-Throughput Synthesis of N3-Acylated Dihydropyrimidines Combining Microwave-Assisted Synthesis and Scavenging Techniques Dallinger, D.; Gorobets, N. Y.; Kappe, C. O.; Org. Lett, 2003, 5, 1205-1208.
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