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SAP
Single Semi-Automated Peptide Synthesizer

SAP

SAP your guarantee for optimal peptide synthesis

The Biotage® SAP is a semi-automated peptide synthesis system that is designed for the synthesis of single peptides.

The synthesis is performed in a glass reaction vessel with glass frit and the scale can be varied from 0.5-15 mmol. Seven different solvents and reagents can be pumped into the reaction flask via an eight-way valve. A digital syringe pump provides accurate dispensing of reagents. The sprinkler head is specially constructed to allow splash-free addition of the reagents and spraying of the wash solvent and also cleaning of the flask. The infinitely variable shaker guarantees a homogeneous mixing of the reactants. The SAP is controlled through an external controller. The controller is equipped with an LCD display with 40 x 16 characters and six function keys. This is used not only for single commands (FILL, REACT, EMPTY…) but for the creation and execution of complex programs. The controller is easy to use and can store 10-programs each with up to 20-steps.

System Components

  • Unit with diluter and integrated 8-way valve 
  • Controller
  • Shaker 30-300 rpm
  • Liquid sensor
  • Sprinkler head
  • Reaction vessel
  • Vacuum-Pump ME2C
  • 10 L waste bottle

Flexibility and User-friendliness
All important system control functions can be used directly in manual mode without a long familiarization period with the complicated control software. Complex single step sequences are linked to a single key command. Complete syntheses-cycles can be processed automatically by linking up to 20 key commands to a program sequence. Ten of these individual programs can be saved on the SAP and remain available to the user.

Controller
The SAP controller is equipped with an LCD display with 40 x 16 characters as well as six function keys. This is used for single commands and the creation and execution of complex programs.

Software

  • Start up screen
  • General function keys
  • System settings
  • Programming menu
  • Menu for manual operation


System Specifications

Synthesizer Synthesizer
Plastic box
Digital syringe pump
Syringe size 10 mL
8-way-valve 4 outlet ports and 4 reagents/solvents ports
Sprinkler head
Shaker 24 V, 30 - 300 rpm
3-way Teflon-valve
Reaction Vessels Glass reactor with glass frit:
25 mL, 50 mL, 100 mL, 250 mL, or 500 mL
Synthesis scale between 0.5 and 15 mmol
Vacuum Vacuum membrane pump ME2C
10L Nalgene vacuum waste bottle
Controller Microprocessor
LC-display with 40x16 characters
10 program files with 20 steps
Automatic fill and wash procedures
Manual mode
Power Requirements Input voltages: 110-220 VAC +/- 10 %
Power supply 24 V max. 150 W
Dimensions
WxDxH 
Synthesizer: 460 mm x 250 mm x 360 mm
Controller: 195 mm x 65 mm x 170 mm
Peptide Synthesis and Purification Brochure
Peptide Synthesis Brochure
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